Detalhe da pesquisa
1.
Hallmarks of neurodegenerative diseases.
Cell
; 186(4): 693-714, 2023 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36803602
2.
Astrocyte-targeted gene delivery of interleukin 2 specifically increases brain-resident regulatory T cell numbers and protects against pathological neuroinflammation.
Nat Immunol
; 23(6): 878-891, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35618831
3.
Spatiotemporal Proteomic Analysis of Stress Granule Disassembly Using APEX Reveals Regulation by SUMOylation and Links to ALS Pathogenesis.
Mol Cell
; 80(5): 876-891.e6, 2020 12 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33217318
4.
Triad of TDP43 control in neurodegeneration: autoregulation, localization and aggregation.
Nat Rev Neurosci
; 22(4): 197-208, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33654312
5.
HDAC6 inhibition restores TDP-43 pathology and axonal transport defects in human motor neurons with TARDBP mutations.
EMBO J
; 40(7): e106177, 2021 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33694180
6.
Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics.
Mol Cell
; 65(6): 1044-1055.e5, 2017 Mar 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28306503
7.
RNA toxicity in non-coding repeat expansion disorders.
EMBO J
; 39(1): e101112, 2020 01 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31721251
8.
PP2A and GSK3 act as modifiers of FUS-ALS by modulating mitochondrial transport.
Acta Neuropathol
; 147(1): 41, 2024 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38363426
9.
Disruption of MAM integrity in mutant FUS oligodendroglial progenitors from hiPSCs.
Acta Neuropathol
; 147(1): 6, 2024 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38170217
10.
Downregulation of PMP22 ameliorates myelin defects in iPSC-derived human organoid cultures of CMT1A.
Brain
; 146(7): 2885-2896, 2023 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36511878
11.
Abnormal energy metabolism in ALS: a key player?
Curr Opin Neurol
; 36(4): 338-345, 2023 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37338894
12.
CRISPR/Cas9 screen in human iPSC-derived cortical neurons identifies NEK6 as a novel disease modifier of C9orf72 poly(PR) toxicity.
Alzheimers Dement
; 19(4): 1245-1259, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35993441
13.
Human Neuromuscular Junction on a Chip: Impact of Amniotic Fluid Stem Cell Extracellular Vesicles on Muscle Atrophy and NMJ Integrity.
Int J Mol Sci
; 24(5)2023 Mar 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36902375
14.
Axonal transport defects and neurodegeneration: Molecular mechanisms and therapeutic implications.
Semin Cell Dev Biol
; 99: 133-150, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31542222
15.
In silico prediction of in vitro protein liquid-liquid phase separation experiments outcomes with multi-head neural attention.
Bioinformatics
; 37(20): 3473-3479, 2021 Oct 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33983381
16.
Increased pyroptosis activation in white matter microglia is associated with neuronal loss in ALS motor cortex.
Acta Neuropathol
; 144(3): 393-411, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35867112
17.
HNRNPK alleviates RNA toxicity by counteracting DNA damage in C9orf72 ALS.
Acta Neuropathol
; 144(3): 465-488, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35895140
18.
F/YGG-motif is an intrinsically disordered nucleic-acid binding motif.
RNA Biol
; 19(1): 622-635, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35491929
19.
Induced pluripotent stem cell-derived motor neurons of CMT type 2 patients reveal progressive mitochondrial dysfunction.
Brain
; 144(8): 2471-2485, 2021 09 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34128983
20.
Spontaneous driving forces give rise to protein-RNA condensates with coexisting phases and complex material properties.
Proc Natl Acad Sci U S A
; 116(16): 7889-7898, 2019 04 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30926670